Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943649 | 1.00 | KDM4E (0.56) | KDM4ESIGMAR1CHRM5CHRM1CHRM2 | |
| SCHEMBL29957083 | 0.72 | KDM4E (0.56) | KDM4ESIGMAR1ALDH1A1CASP6GAA | |
| SCHEMBL977989 | 0.72 | KDM4E (0.58) | KDM4ESIGMAR1CHRM5CHRM3ALDH1A1 | |
| SCHEMBL12250826 | 0.71 | MEN1 (0.40) | KDM4ESIGMAR1CHRM5CHRM1CHRM2 | |
| SCHEMBL1083799 | 0.71 | MEN1 (0.40) | KDM4ESIGMAR1CHRM5CHRM1CHRM2 | |
| SCHEMBL12250827 | 0.71 | MEN1 (0.40) | KDM4ESIGMAR1CHRM5CHRM1CHRM2 | |
| SCHEMBL29956109 | 0.70 | KDM4E (0.50) | KDM4ESIGMAR1ALDH1A1CASP6GAA | |
| SCHEMBL979295 | 0.69 | SIGMAR1 (1.00) | KDM4ESIGMAR1CHRM5CHRM1CHRM2 | |
| SCHEMBL19046434 | 0.69 | KDM4E (0.77) | KDM4ESIGMAR1ALDH1A1CASP6GAA | |
| SCHEMBL27737514 | 0.69 | SIGMAR1 (0.45) | SIGMAR1CHRM1CHRM2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |