Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 7/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436539 | 1.00 | PPARG (0.39) | PPARGCAPN1LGALS3CA12CA1 | |
| SCHEMBL29307606 | 0.77 | PPARG (0.38) | PPARGCAPN1LGALS3CA12CA1 | |
| SCHEMBL9127580 | 0.76 | TSHR (0.47) | CAPN1LGALS3CTSLLMNACTSB | |
| SCHEMBL29902551 | 0.76 | TSHR (0.47) | CAPN1LGALS3CTSLLMNACTSB | |
| SCHEMBL9436547 | 0.76 | TSHR (0.47) | CAPN1LGALS3CTSLLMNACTSB | |
| SCHEMBL11184816 | 0.73 | CAPN1 (0.49) | PPARGCAPN1CTSLLMNACTSB | |
| SCHEMBL11170652 | 0.73 | CAPN1 (0.41) | PPARGCAPN1CA12CA1CA2 | |
| SCHEMBL11184819 | 0.72 | CAPN1 (0.40) | PPARGCAPN1CA12CA1CA2 | |
| SCHEMBL9436546 | 0.71 | — | — | |
| SCHEMBL9436545 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296615-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5256807-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1993-10-26 | — | — | US | disclosed |
| US-5183910-A | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1993-02-02 | — | — | US | disclosed |
| US-5097049-A | PROCESS AND INTERMEDIATES FOR CHIRAL EPOXIDES | ELI LILLY AND COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0455473-A1 | Process and intermediates for chiral epoxides | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |