Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27104270 | 0.89 | CAPN1 (0.34) | PPARGCAPN1AHCYCTSLLMNA | |
| SCHEMBL21943698 | 0.83 | AHCY (0.44) | AHCYLGALS3ALDH1A1 | |
| SCHEMBL6666772 | 0.81 | PPM1B (0.41) | AHCYALDH1A1 | |
| SCHEMBL27766467 | 0.79 | AHCY (0.45) | AHCYLMNAALDH1A1 | |
| SCHEMBL14317077 | 0.79 | AHCY (0.45) | AHCYLMNAALDH1A1 | |
| SCHEMBL2189191 | 0.78 | TSHR (0.45) | CAPN1CTSLLMNACTSBCTSG | |
| SCHEMBL2189182 | 0.78 | TSHR (0.45) | CAPN1CTSLLMNACTSBCTSG | |
| SCHEMBL9436540 | 0.77 | PPARG (0.39) | PPARGCAPN1CA12CA1CA2 | |
| SCHEMBL9436539 | 0.77 | PPARG (0.39) | PPARGCAPN1CA12CA1CA2 | |
| SCHEMBL21121284 | 0.76 | NAAA (0.43) | PPARGAHCYMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037378-B2 | Variant CD58 domains and uses thereof | NOVARTIS AG (CH) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037378-B2 | Variant CD58 domains and uses thereof | CD2, CD58, CD2BP2 | PPARG 4780/4885CAPN1 2140/4885CA12 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.