Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533929 | 0.87 | SLC9A1 (0.56) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL11768216 | 0.86 | KDM4E (0.47) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL11708034 | 0.86 | KDM4E (0.51) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL9436719 | 0.85 | SLC9A1 (0.68) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL9196797 | 0.84 | SLC9A1 (0.66) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL11536336 | 0.83 | SLC9A1 (0.50) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL9194834 | 0.82 | SLC9A1 (0.80) | SLC9A1MMP2 | |
| Hydrochloric Acid SCHEMBL9436759 | 0.81 | SLC9A1 (0.78) | SLC9A1MMP2 | |
| SCHEMBL9436694 | 0.81 | NPSR1 (0.56) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL11710040 | 0.80 | DRD2 (0.51) | KDM4EGAAHSD17B10POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |