Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL9263052 | 0.88 | NPC1 (0.43) | TDP1ALDH1A1GAAHSD17B10RAB9A | |
| SCHEMBL28004 | 0.83 | ALDH1A1 (0.58) | MAPTIL1RNALDH1A1GAAHSD17B10 | |
| SCHEMBL29453108 | 0.83 | ALDH1A1 (0.58) | MAPTIL1RNALDH1A1GAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL35358 | 0.82 | ALDH1A1 (0.56) | MAPTIL1RNALDH1A1GAAHSD17B10 | |
| Isophthalic Acid SCHEMBL15570863 | 0.81 | KMO (0.51) | MAPTALDH1A1GAAHSD17B10AKR1C3 | |
| Isophthalic Acid SCHEMBL15572812 | 0.81 | KMO (0.51) | MAPTALDH1A1GAAHSD17B10AKR1C3 | |
| Morpholine SCHEMBL7334021 | 0.80 | KMO (0.48) | MAPTRAB9ANPC1KMOSMN1; SMN2 | |
| 3-Hydroxybenzoic Acid SCHEMBL5893711 | 0.78 | CA12 (0.65) | MAPTALDH1A1RAB9AKMOCA1 | |
| Benzoic Acid SCHEMBL7026585 | 0.77 | TSHR (0.56) | MAPTALDH1A1GAAHSD17B10RAB9A | |
| Benzoic Acid SCHEMBL9285867 | 0.75 | TSHR (0.54) | MAPTALDH1A1GAAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5091394-A | BENZOYLGUANIDINES, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |