Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437295 | 0.90 | MAPT (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10654584 | 0.84 | MAPT (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5871351 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2127522 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL183637 | 0.83 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL29450286 | 0.83 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10358996 | 0.82 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AHPGD | |
| Ethylene SCHEMBL10653813 | 0.82 | MAPT (0.43) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27606506 | 0.82 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10654314 | 0.81 | MAPT (0.43) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281602-A | Pharmaceuticals | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |