SCHEMBL183637

SCHEMBL183637

CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
ADORA1 P30542 1/20 0.43
ALDH1A1 P00352 5/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
GLA P06280 1/20 0.39
RECQL P46063 1/20 0.39
GAA P10253 1/20 0.39
NR1H2 P55055 1/20 0.39
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
ESR2 Q92731 1/20 0.37
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRB P10828 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450286 1.00 MAPT (0.46) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL29974438 0.92 MAPT (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL183693 0.92 MAPT (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL10654584 0.89 MAPT (0.46) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL20015491 0.88 MEN1 (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL183757 0.88 MEN1 (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL4760227 0.87 ADORA1 (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL22615393 0.87 ADORA1 (0.44) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL1224464 0.86 MAPT (0.48) MAPTADORA1ALDH1A1MEN1KMT2A
SCHEMBL1224468 0.86 MAPT (0.48) MAPTADORA1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113637001-A Synthesis method of droperidol intermediate 安康市农业科学研究院 2021-11-12 CN claimed
CN-106632318-B A kind of tetrahydropyridine miazines compound and its preparation method and application 广东环境保护工程职业学院 2018-07-31 CN claimed
CN-106632318-A Tetrahydropyridopyrimidine compound, preparation method therefor and application of tetrahydropyridopyrimidine compound 广东环境保护工程职业学院 2017-05-10 CN claimed
EP-4294800-B1 APOL1 INHIBITORS AND METHODS OF USE MAZE THERAPEUTICS INC (US) 2026-05-06 EP disclosed
EP-4736854-A2 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4705293-A1 SPIRO-HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF Amgen Inc. (US) 2026-03-11 EP disclosed
US-12569485-B2 SMARCA inhibitors and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC (US) 2026-03-05 US disclosed
EP-4514473-B1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL MYERS SQUIBB CO (US) 2026-02-18 EP disclosed
US-20250346600-A1 TRICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2025-11-13 US disclosed
EP-4644396-A1 TOLL-LIKE RECEPTOR INHIBITOR, AND PREPARATION THEREFOR AND APPLICATION THEREOF Visionpharma (Nantong) Co., Ltd (CN) 2025-11-05 EP disclosed
EP-0989993-A1 TARTRATE SALT OF A SUBSTITUTED DIPEPTIDE AS GROWTH HORMONE SECRETAGOGUE Pfizer Products Inc. (US) 2000-04-05 EP disclosed
WO-1999065488-A1 THERAPEUTIC COMBINATIONS OF (SELECTIVE) ESTROGEN RECEPTOR MODULATORS (SERM) AND GROWTH HORMONE SECRETAGOGUES (GHS) FOR TREATING MUSCULOSKELETAL FRAILTY PFIZER PRODUCTS INC. (US) 1999-12-23 WO disclosed
WO-1999003832-A1 PIPERIDINE OLIGOMERS AND COMBINATORIAL LIBRARIES THEREOF PHYTERA SYMBION APS (DK) 1999-01-28 WO disclosed
WO-1998058948-A1 TARTRATE SALT OF A SUBSTITUTED DIPEPTIDE AS GROWTH HORMONE SECRETAGOGUE PFIZER PRODUCTS INC. (US) 1998-12-30 WO disclosed
EP-0869968-A1 GROWTH-HORMONE SECRETAGOGUES PFIZER INC. (US) 1998-10-14 EP disclosed
US-5756508-A Muscarine antagonists MERCK & CO., INC. (US) 1998-05-26 US disclosed
WO-1997024369-A1 GROWTH-HORMONE SECRETAGOGUES PFIZER INC. (US) 1997-07-10 WO disclosed
WO-1997016192-A1 MUSCARINE ANTAGONISTS MERCK & CO., INC. (US) 1997-05-09 WO disclosed
US-5376666-A Hypotensive agents, angiotension antagonist, enzyme inhibitors , treating congestive heart failure THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS3, LGALS1, LGALS2 MAPT 2059/4885ADORA1 3891/4885ALDH1A1 1833/4885
US-12569485-B2 SMARCA inhibitors and uses thereof SMARCC1, SMARCC2, SMARCA2 MAPT 4757/4885ADORA1 2743/4885ALDH1A1 3410/4885
US-20250346600-A1 TRICYCLIC DERIVATIVES AND RELATED USES WRN, RECQL, BLM MAPT 4614/4885ADORA1 2537/4885ALDH1A1 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.