Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490490 | 0.81 | TYR (0.55) | CYP3A4APPCYP2C9CYP2C19PTGS2 | |
| SCHEMBL29429345 | 0.81 | TYR (0.55) | CYP3A4APPCYP2C9CYP2C19PTGS2 | |
| SCHEMBL1678601 | 0.80 | PTGS1 (0.38) | PTGS2PTGS1 | |
| SCHEMBL28745580 | 0.79 | PTGS1 (0.42) | CYP3A4APPCYP2C9CYP2C19PTGS2 | |
| SCHEMBL16219361 | 0.78 | PTGS1 (0.52) | CYP3A4APPCYP2C9CYP2C19PTGS2 | |
| SCHEMBL16790333 | 0.77 | FFAR1 (0.37) | CYP3A4TYRMEN1KMT2ACYP1A2 | |
| SCHEMBL490883 | 0.77 | PTGS2 (0.60) | CYP3A4APPCYP2C9CYP2C19PTGS2 | |
| SCHEMBL26617178 | 0.76 | TYR (0.40) | TYRADRA2B | |
| SCHEMBL25255901 | 0.75 | PTGS2 (0.50) | CYP3A4APPPTGS2PTGS1AKR1C3 | |
| SCHEMBL740967 | 0.75 | CYP2C9 (0.48) | CYP3A4APPCYP2C9CYP2C19PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366958-A | Localized delivery using fibronectin conjugates | THE LIPOSOME COMPANY, INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-4708861-A | BIOACTIVE AGENT SEQUESTERED AND RELEASED | THE LIPOSOME COMPANY, INC. (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0114818-B1 | IMMUNOASSAY FOR CARBOHYDRATE ANTIGENIC DETERMINANT | CENTOCOR, INC. (US) | 1987-08-12 | — | — | EP | disclosed |