Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.40 |
| ▸ | METAP2 | P50579 | 4/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333758 | 1.00 | REN (0.40) | RENMETAP2METAP1CTSKLNPEP | |
| SCHEMBL7339021 | 0.98 | REN (0.40) | RENMETAP2METAP1CTSKLNPEP | |
| SCHEMBL7333234 | 0.87 | REN (0.39) | RENMETAP2METAP1CTSKLNPEP | |
| SCHEMBL5709586 | 0.83 | REN (0.44) | RENMETAP2METAP1CTSKCTSL | |
| Citric Acid SCHEMBL7333217 | 0.80 | REN (0.43) | RENMETAP2METAP1LNPEP | |
| SCHEMBL7338827 | 0.77 | REN (0.36) | RENMETAP2METAP1 | |
| Citric Acid SCHEMBL9437491 | 0.77 | REN (0.41) | RENMETAP2METAP1 | |
| Citric Acid SCHEMBL7333760 | 0.77 | REN (0.41) | RENMETAP2METAP1 | |
| Citric Acid SCHEMBL7339025 | 0.77 | REN (0.41) | RENMETAP2METAP1 | |
| Citric Acid SCHEMBL7333742 | 0.74 | REN (0.39) | RENMETAP2METAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310740-A | Congestive heart failure, hypotensive agents, antiglaucoma agents; side effect reduction | ABBOTT LABORATORIES (US) | 1994-05-10 | — | — | US | disclosed |