Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.81 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.69 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 8/20 | 0.56 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437570 | 1.00 | ALOX5 (0.81) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL22819051 | 0.89 | ALOX5 (0.77) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL6790600 | 0.86 | ALOX5 (0.68) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL6790597 | 0.86 | ALOX5 (0.68) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL13521556 | 0.86 | ALOX5 (0.68) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL2131615 | 0.83 | DAPK3 (0.75) | ALOX5NOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL2131623 | 0.83 | DAPK3 (0.75) | ALOX5NOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL4691058 | 0.83 | DAPK3 (0.75) | ALOX5NOTUMKDM4EALDH1A1MAPT | |
| SCHEMBL24534666 | 0.82 | ALOX5 (0.64) | ALOX5NOTUMERO1AKDM4EALDH1A1 | |
| SCHEMBL25526265 | 0.82 | PLCG2 (0.64) | ALOX5NOTUMERO1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340802-A | Central nervous system disorders | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |