Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437849 | 0.94 | HTR1A (0.48) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437911 | 0.93 | HTR1A (0.49) | HTR1AHTR2CGABRA1GABRA5 | |
| SCHEMBL9437723 | 0.93 | HTR1A (0.52) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437879 | 0.89 | HTR1A (0.52) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437784 | 0.89 | HTR1A (0.54) | HTR1AHTR2CGABRA1GABRA5 | |
| SCHEMBL9437689 | 0.83 | HTR1A (0.50) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437919 | 0.80 | HTR1A (0.46) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437713 | 0.78 | HTR1A (0.45) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437745 | 0.77 | HTR1A (0.49) | HTR1AHTR2CGABRA1GABRA5HTR1D | |
| SCHEMBL9437871 | 0.77 | HTR1A (0.49) | HTR1AHTR2CGABRA1GABRA5HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |