Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9085541 | 0.94 | HTR1A (0.40) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL9532032 | 0.90 | ALDH1A1 (0.43) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL28956491 | 0.90 | ALDH1A1 (0.43) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL17532416 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL10948563 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL17532423 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL5427844 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL17532412 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AHTTRAB9ASMN1; SMN2 | |
| SCHEMBL11510536 | 0.76 | HTT (0.51) | ALDH1A1HTR1AMEN1KMT2ARECQL | |
| SCHEMBL9516183 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTR1ADRD2HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |