Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL988008 | 0.87 | TSHR (0.71) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL27547121 | 0.84 | TSHR (0.67) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL27906745 | 0.84 | TSHR (0.67) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL28236599 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL9345627 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL9345632 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL27906743 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL3634909 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL27491776 | 0.81 | TSHR (0.62) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL11224450 | 0.79 | TSHR (0.83) | TSHRTP53CYP2C9PDE4ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344464-A | Hair dyes with para-phenylenediamine and N,N*-diphenyl-alkylenediamine dye precursors for keratin fibers | L'OREAL (FR) | 1994-09-06 | — | — | US | disclosed |
| US-5137538-A | P-Phenylenediamine and N,N'-diphenylalkylenediamines; uniform color on bleached or permed hair | L'OREAL (FR) | 1992-08-11 | — | — | US | disclosed |