Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437713 | 0.97 | HTR1A (0.45) | HTR1AMAOBBCHEACHEHTR2C | |
| SCHEMBL9437720 | 0.96 | HTR1A (0.51) | HTR1AMAOBBCHEACHEHTR2C | |
| SCHEMBL9437871 | 0.94 | HTR1A (0.49) | HTR1AMAOBBCHEACHEHTR2C | |
| SCHEMBL9437919 | 0.93 | HTR1A (0.46) | HTR1AMAOBHTR2CGABRA1GABRA5 | |
| SCHEMBL9437745 | 0.93 | HTR1A (0.49) | HTR1AMAOBBCHEACHEHTR2C | |
| SCHEMBL9593875 | 0.86 | HTR1A (0.50) | HTR1AHTR2CGABRA1GABRA5 | |
| SCHEMBL9437846 | 0.81 | HTR1A (0.46) | HTR1AHTR2CGABRA1GABRA5 | |
| SCHEMBL9437784 | 0.81 | HTR1A (0.54) | HTR1AACHEHTR2CGABRA1GABRA5 | |
| SCHEMBL9437911 | 0.81 | HTR1A (0.49) | HTR1AACHEHTR2CGABRA1GABRA5 | |
| SCHEMBL9437801 | 0.81 | HTR1A (0.40) | HTR1AHTR2CGABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |