Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437691 | 0.96 | SIGMAR1 (0.49) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9452079 | 0.87 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL9437835 | 0.86 | SIGMAR1 (0.52) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9556475 | 0.83 | SIGMAR1 (0.48) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437912 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL9437861 | 0.82 | SIGMAR1 (0.48) | SIGMAR1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL9437705 | 0.81 | SIGMAR1 (0.46) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437850 | 0.81 | SIGMAR1 (0.54) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437780 | 0.81 | SIGMAR1 (0.53) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9437909 | 0.80 | HTR1A (0.46) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |