Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438094 | 1.00 | RAB9A (0.47) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9438085 | 0.91 | NPC1 (0.55) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL10587639 | 0.91 | LMNA (0.44) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL10587610 | 0.88 | MEN1 (0.41) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11605009 | 0.81 | CYP1A2 (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11605334 | 0.81 | MAPT (0.51) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11398684 | 0.81 | CYP1A2 (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL7928173 | 0.81 | CYP1A2 (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL10812766 | 0.80 | ADORA2A (0.46) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL35556 | 0.79 | P2RY2 (0.60) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342974-A | Reacting 1,4,5,8-tetrachloroanthraquione with monohalogenated aniline in presence of carboxylic acid salt, benzyl alcohol and copper catalyst | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0323184-B1 | Halogenated anthraquinones useful as near infrared absorbing optical filters, and method of making them | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | disclosed |