SCHEMBL2423618

SCHEMBL2423618

O=P(O)(O)Oc1cccc(O)c1.c1ccc(Pc2ccccc2)cc1.c1ccc(Pc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.55
INPPL1 O15357 4/20 0.41
INPP5A Q14642 4/20 0.41
CYP3A4 P08684 1/20 0.40
POLB P06746 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
INPP5B P32019 1/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
PDE3A Q14432 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
DRD3 P35462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL999412 0.92 SRC (0.64) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL133534 0.87 SRC (0.59) SRCINPPL1INPP5ACYP3A4POLB
SCHEMBL29743077 0.87 SRC (0.59) SRCINPPL1INPP5ACYP3A4POLB
Biphenyl SCHEMBL6141288 0.85 SRC (0.60) SRCINPPL1INPP5ACYP3A4ESR1
SCHEMBL20854529 0.85 SRC (0.58) SRCINPPL1INPP5ACYP3A4POLB
Naphthalene SCHEMBL9438226 0.83 SRC (0.57) SRCINPPL1INPP5ACYP3A4ESR1
Phenyl Dihydrogen Phosphate SCHEMBL1457869 0.83 SRC (0.73) SRCINPPL1INPP5ACYP3A4INPP5B
Phenyl Dihydrogen Phosphate SCHEMBL6767193 0.83 SRC (0.73) SRCINPPL1INPP5ACYP3A4INPP5B
Phenyl Dihydrogen Phosphate SCHEMBL27723079 0.82 SRC (0.70) SRCINPPL1INPP5ACYP3A4INPP5B
Resorcinol SCHEMBL2423620 0.81 CA2 (0.48) CYP3A4ESR1KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026303-B2 Halogen-free flame retardant compositions, thermoplastic compositions comprising the same and methods of producing the compositions ICL-IP AMERICA INC. (US) 2011-09-27 US disclosed
US-20100010128-A1 Halogen-Free Flame Retardant Compositions, Thermoplastic Compositions Comprising the Same and Methods of Producing the Compositions ICL-IP AMERICA INC. 2010-01-14 US disclosed
EP-1976913-A1 HALOGEN-FREE FLAME RETARDANT COMPOSITIONS, THERMOPLASTIC COMPOSITIONS COMPRISING THE SAME AND METHODS OF PRODUCING THE COMPOSITIONS Supresta LLC (US) 2008-10-08 EP disclosed
WO-2007081904-A1 HALOGEN-FREE FLAME RETARDANT COMPOSITIONS, THERMOPLASTIC COMPOSITIONS COMPRISING THE SAME AND METHODS OF PRODUCING THE COMPOSITIONS SUPRESTA LLC (US) 2007-07-19 WO disclosed