Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383363 | 0.88 | MEN1 (0.47) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL6674482 | 0.88 | MEN1 (0.47) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL9721188 | 0.86 | POLB (0.43) | RAB9APOLBMEN1NPC1BLM | |
| Trifluoromethanesulfonic Acid SCHEMBL15268656 | 0.83 | MEN1 (0.51) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL29361182 | 0.83 | MEN1 (0.63) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL9096221 | 0.83 | MEN1 (0.63) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL94397 | 0.82 | POLB (0.52) | RAB9APOLBMEN1NPC1BLM | |
| Hydrochloric Acid SCHEMBL6769348 | 0.81 | MEN1 (0.61) | RAB9APOLBMEN1NPC1BLM | |
| SCHEMBL10483630 | 0.81 | CRHBP (0.45) | RAB9APOLBMEN1NPC1BLM | |
| Sulfuric Acid SCHEMBL10339575 | 0.80 | NQO2 (0.48) | RAB9APOLBMEN1NPC1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294540-A | Quantitative assay in aqueous fluids; using tetrazolium salt, NAD+, alcohol dehydrogenase, a phenolthiazine methosulfate and poly(methyl acrylate-co-2-sulfo-1,1-dimethylethyl acrylamide-co-2-acetoacetoxyethyl methacrylate | EASTMAN KODAK COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0464942-A1 | Ethanol analytical element | EASTMAN KODAK COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |