Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361182 | 0.98 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9096221 | 0.98 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9APOLB | |
| Iodide SCHEMBL9231924 | 0.81 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9438445 | 0.81 | RAB9A (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL19400976 | 0.80 | KMT2A (0.50) | MEN1KMT2ANPC1RAB9APOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL15268656 | 0.80 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL13621632 | 0.80 | RAB9A (0.74) | MEN1KMT2ANPC1RAB9APOLB | |
| Morpholine SCHEMBL9227093 | 0.79 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6674482 | 0.79 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL29383363 | 0.79 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040231995-A1 | Printed circuit boards and the methods of their production | HITACHI, LTD. (JP) | 2004-11-25 | — | — | US | disclosed |