Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439000 | 1.00 | ACE (0.66) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9439005 | 1.00 | ACE (0.66) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL683203 | 0.90 | ACE (0.67) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL683187 | 0.90 | ACE (0.67) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL5598999 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL28425123 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL683210 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL1269121 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL22372411 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA | |
| Perindoprilat SCHEMBL28425122 | 0.90 | ACE (0.80) | ACEMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348944-A | Hypotensive agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |