SCHEMBL9439348

SCHEMBL9439348

O=C(O)c1ccc(COCc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
TP53 P04637 1/20 0.57
TSHR P16473 1/20 0.57
NR4A2 P43354 3/20 0.57
NR4A1 P22736 1/20 0.57
NR4A3 Q92570 1/20 0.57
RXRA P19793 6/20 0.56
RXRB P28702 5/20 0.56
NPC1 O15118 1/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA3 P07451 1/20 0.54
TYR P14679 1/20 0.54
DRD1 P21728 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27832128 0.94 NR4A1 (0.67) ALDH1A1TSHRNR4A2NR4A1NR4A3
SCHEMBL21533380 0.92 ALDH1A1 (0.61) ALDH1A1TP53TSHRNR4A2NR4A1
Terephthalic Acid SCHEMBL11039705 0.91 NR4A2 (0.69) ALDH1A1TSHRNR4A2NR4A1NR4A3
SCHEMBL13660529 0.90 ALDH1A1 (0.59) ALDH1A1TP53TSHRNR4A2NR4A1
SCHEMBL24474396 0.89 ALDH1A1 (0.62) ALDH1A1TP53TSHRNR4A2NR4A1
SCHEMBL28860807 0.87 ALDH1A1 (0.61) ALDH1A1TP53TSHRNR4A2NR4A1
SCHEMBL1749635 0.87 ALDH1A1 (0.61) ALDH1A1NR4A2NR4A1NR4A3RXRA
SCHEMBL10553092 0.86 ALDH1A1 (0.59) ALDH1A1NR4A2NR4A1NR4A3RXRA
SCHEMBL4739829 0.86 ALDH1A1 (0.59) ALDH1A1TP53TSHRNR4A2NR4A1
SCHEMBL11439105 0.84 ALDH1A1 (0.57) ALDH1A1TP53TSHRNR4A2NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102229573-B 1-(1,2,4-triazole-1-group)ketoxime ethers and its application in preparation of bactericide UNIV HUNAN 2013-03-13 CN disclosed
EP-0440995-B1 Process for preparing 1-octene SHELL INT RESEARCH (NL) 1994-05-11 EP disclosed
EP-0440995-A1 Process for preparing 1-octene SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-14 EP disclosed
US-5030792-A Process for preparing 1-octene SHELL OIL COMPANY (US) 1991-07-09 US disclosed
US-4721808-A Process for purification of crude p-hydroxymethylbenzoic acid AMOCO CORPORATION (US) 1988-01-26 US disclosed
US-4457814-A TO P-HYDROXYMETHYLBENZOIC ACID STANDARD OIL COMPANY (INDIANA) (US) 1984-07-03 US disclosed
US-4402805-A REDUCTION OF TEREPHTHALIC ACID STANDARD OIL COMPANY INDIANA (US) 1983-09-06 US disclosed
US-4159617-A Resilient polyester fibers FIBER INDUSTRIES, INC. (US) 1979-07-03 US disclosed
US-4031692-A PICK RESISTANT POLYESTER TWIST FIBER INDUSTRIES, INC. (US) 1977-06-28 US disclosed