Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | AR | P10275 | 9/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304933 | 0.91 | BCHE (0.77) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL15501211 | 0.87 | NPC1 (0.74) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL6756956 | 0.84 | BCHE (0.67) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL6754436 | 0.84 | BCHE (0.67) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL15501159 | 0.83 | EPHX2 (0.71) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL6754338 | 0.83 | BCHE (0.65) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL6757846 | 0.83 | BCHE (0.65) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL8098342 | 0.83 | RAB9A (0.82) | SMN1; SMN2LMNAKMT2AMAPTHTT | |
| SCHEMBL11475158 | 0.82 | BCHE (1.00) | SMN1; SMN2LMNAKMT2AMEN1HPGD | |
| SCHEMBL14304969 | 0.82 | BCHE (0.73) | SMN1; SMN2LMNAKMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294629-A | Benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0370436-A2 | Novel benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |