Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 9/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304933 | 0.90 | BCHE (0.77) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5503497 | 0.88 | LMNA (0.85) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9439554 | 0.87 | SMN1; SMN2 (0.71) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14304969 | 0.87 | BCHE (0.73) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL425175 | 0.86 | RAB9A (1.00) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2948524 | 0.84 | RAB9A (0.91) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6754436 | 0.83 | BCHE (0.67) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6756956 | 0.83 | BCHE (0.67) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11535096 | 0.83 | NPC1 (0.88) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL21639229 | 0.83 | NPC1 (0.88) | NPC1RAB9ALMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2163949-B1 | Developer for lithographic printing plate precursor and process for producing lithographic printing plate | FUJIFILM CORP (JP) | 2014-03-12 | — | — | EP | disclosed |