Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809550 | 0.87 | TSHR (0.39) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL8564392 | 0.85 | SOAT1 (0.41) | SOAT1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1809548 | 0.71 | LMNA (0.40) | ALDH1A1KMT2AMEN1POLBTSHR | |
| SCHEMBL14008396 | 0.68 | APOBEC3A (0.36) | ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL1812933 | 0.65 | MAPK1 (0.38) | KMT2AL3MBTL1MEN1TSHRCA12 | |
| Diethyl Pyrocarbonate SCHEMBL30366210 | 0.63 | SOAT1 (1.00) | SOAT1ALDH1A1TSHR | |
| Diethyl Pyrocarbonate SCHEMBL15582 | 0.63 | SOAT1 (1.00) | SOAT1ALDH1A1TSHR | |
| SCHEMBL10353821 | 0.63 | TSHR (0.70) | SOAT1ALDH1A1KMT2AL3MBTL1MEN1 | |
| SCHEMBL14008389 | 0.63 | MEN1 (0.36) | KMT2AMEN1 | |
| SCHEMBL11419878 | 0.62 | SMN1; SMN2 (0.53) | SOAT1ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327263-B1 | Hair growth stimulation with nitroxide and other radicals | PROCTOR PETER H (US) | 1994-09-07 | — | — | EP | claimed |
| US-20120046461-A1 | STEROIDAL ANTI-HORMONE HYBRIDS | NORTHEASTERN UNIVERSITY (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046461-A1 | STEROIDAL ANTI-HORMONE HYBRIDS | ESRRA, ESRRB, NR5A1 | SOAT1 2175/4885ALDH1A1 2752/4885KMT2A 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.