Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439634 | 0.87 | SOAT1 (0.41) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL10271548 | 0.86 | ALDH1A1 (0.40) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL1809548 | 0.83 | LMNA (0.40) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL14008396 | 0.72 | APOBEC3A (0.36) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL8564392 | 0.71 | SOAT1 (0.41) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL14008389 | 0.67 | MEN1 (0.36) | MEN1KMT2AGAA | |
| SCHEMBL12150575 | 0.66 | KDM4E (0.43) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL1812932 | 0.62 | MAPK1 (0.38) | TSHRMAPK1CA12CA1CA2 | |
| SCHEMBL28679523 | 0.62 | CYP1A2 (0.40) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL21950893 | 0.62 | CA12 (0.48) | TSHRMAPK1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473795-B2 | Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2009-01-06 | — | — | US | claimed |
| EP-1438277-B1 | RECYCLE OF NITROXYL-CONTAINING STREAMS AT LOW TEMPERATURE | UNIROYAL CHEM CO INC (US) | 2007-03-07 | — | — | EP | claimed |
| US-20060155140-A1 | Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors | UNIROYAL CHEMICAL COMPANY, INC A CORPORATION OF THE STATE OF DELAWARE | 2006-07-13 | — | — | US | claimed |
| US-7045647-B2 | Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2006-05-16 | — | — | US | claimed |
| US-20050113625-A1 | Composition and method for inhibiting polymerization and polymer growth | UNIROYAL CHEMICAL COMPANY, INC. | 2005-05-26 | — | — | US | claimed |
| US-20050113626-A1 | Composition and method for inhibiting polymerization and polymer growth | UNIROYAL CHEMICAL COMPANY, INC., A CORPORATION OF THE STATE OF DELAWARE | 2005-05-26 | — | — | US | claimed |
| EP-1438277-A2 | RECYCLE OF NITROXYL-CONTAINING STREAMS AT LOW TEMPERATURE | Uniroyal Chemical Company, Inc. (US) | 2004-07-21 | — | — | EP | claimed |
| US-20040010159-A1 | Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors | ADDIVANT USA, LLC | 2004-01-15 | — | — | US | claimed |
| US-20020123658-A1 | Recycle of nitroxyl-containing streams at low temperature | CROMPTON CORPORATION | 2002-09-05 | — | — | US | claimed |
| EP-1235885-A1 | COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH | Uniroyal Chemical Company, Inc. (US) | 2002-09-04 | — | — | EP | claimed |
| WO-2002010100-A2 | RECYCLE OF NITROXYL-CONTAINING STREAMS AT LOW TEMPERATURE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2002-02-07 | — | — | WO | claimed |
| WO-2001040404-A1 | COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-06-07 | — | — | WO | claimed |
| US-7943809-B2 | Composition and method for inhibiting polymerization and polymer growth | CHEMTURA CORPORATION (US) | 2011-05-17 | — | — | US | disclosed |
| US-7728083-B1 | Aromatic sulfonic acids, amines and nitrophenols in combination with nitroxyl radical-containing compounds or C-nitrosoanilines as polymerization inhibitors | CHEMTURA CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-20100127218-A1 | AROMATIC SULFONIC ACIDS, AMINES AND NITROPHENOLS IN COMBINATION WITH NITROXYL RADICAL-CONTAINING COMPOUNDS OR C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORPORATION (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100093897-A1 | COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH | CHEMTURA CORPORATION (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2002010100-A2 | RECYCLE OF NITROXYL-CONTAINING STREAMS AT LOW TEMPERATURE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2002-02-07 | — | — | WO | disclosed |
| US-6344560-B1 | SOLUBILITY OF NITROXYL IN AROMATIC SOLVENT AND NITROAROMATIC COMPOUND | UNIROYAL CHEMICAL COMPANY, INC. | 2002-02-05 | — | — | US | disclosed |
| WO-2001040404-A1 | COMPOSITION AND METHOD FOR INHIBITING POLYMERIZATION AND POLYMER GROWTH | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001040319-A2 | INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS | CROMPTON CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113625-A1 | Composition and method for inhibiting polymerization and polymer growth | ELL, ELOVL1, ELOVL5 | TSHR 4803/4885MAPK1 2157/4885CA12 4419/4885 |
| US-20050113626-A1 | Composition and method for inhibiting polymerization and polymer growth | ELL, ELOVL1, ELOVL5 | TSHR 4803/4885MAPK1 2157/4885CA12 4419/4885 |
| US-20060155140-A1 | Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors | SQOR, NQO1, NQO2 | TSHR 4884/4885MAPK1 1391/4885CA12 4848/4885 |
| US-20020123658-A1 | Recycle of nitroxyl-containing streams at low temperature | NQO2, NOS2, NOS1 | TSHR 4723/4885MAPK1 1903/4885CA12 4755/4885 |
| US-20040010159-A1 | Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors | SQOR, NQO1, NQO2 | TSHR 4883/4885MAPK1 1332/4885CA12 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.