Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435605 | 1.00 | NMT2 (0.46) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL7434798 | 1.00 | NMT2 (0.46) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL7435642 | 1.00 | NMT2 (0.46) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL7441035 | 1.00 | NMT2 (0.46) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9614810 | 0.93 | ITGB1 (0.45) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL7318647 | 0.90 | NMT2 (0.40) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL7427745 | 0.86 | PLG (0.39) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL15870650 | 0.86 | PLA2G2A (0.53) | NMT2NMT1SLC6A5MEN1ALDH1A1 | |
| SCHEMBL6448450 | 0.84 | PLA2G2A (0.54) | MEN1LMNAKMT2AEPHX2NFKB1 | |
| SCHEMBL6448445 | 0.84 | PLA2G2A (0.54) | MEN1LMNAKMT2AEPHX2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494248-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | — | 1992-08-26 | — | — | EP | claimed |
| EP-0494248-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-15 | — | — | EP | claimed |
| WO-1991004746-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-04-18 | — | — | WO | claimed |
| US-5332726-A | Anticoagulant | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1991004746-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-04-18 | — | — | WO | disclosed |