SCHEMBL9439902

SCHEMBL9439902

CC1CCC(N=C=O)CC1.N=C=O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
APLNR P35414 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28120055 1.00 ALDH1A1 (0.50) ALDH1A1APLNRCYP3A4
SCHEMBL28853844 1.00 ALDH1A1 (0.50) ALDH1A1APLNRCYP3A4
SCHEMBL1493050 0.93 ALDH1A1 (0.56) ALDH1A1APLNRCYP3A4
SCHEMBL1992984 0.93 ALDH1A1 (0.56) ALDH1A1APLNRCYP3A4
SCHEMBL20537320 0.88 ALDH1A1 (0.62) ALDH1A1APLNRCYP3A4
SCHEMBL21065562 0.86 ALDH1A1 (0.50) ALDH1A1APLNRCYP3A4
Methane SCHEMBL6901563 0.85 ALDH1A1 (0.59) ALDH1A1APLNRCYP3A4
SCHEMBL20782935 0.84 ALDH1A1 (0.60) ALDH1A1APLNRCYP3A4
SCHEMBL150431 0.84 ALDH1A1 (0.74) ALDH1A1APLNRCYP3A4
Cyanate SCHEMBL28834574 0.83 ALDH1A1 (0.46) ALDH1A1APLNRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336749-A Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-08-09 US disclosed
EP-0394058-B1 ALICYCLIC DIAMINES, ALICYCLIC DIISOCYANATES AND POLYISOCYANATO-ISOCYANURATES AND METHOD FOR THE PREPARATION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-25 EP disclosed
US-5210286-A Hydrogenation of corresponding aromatic compound, reaction with phosgene MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-11 US disclosed
US-5126426-A Catalytic hydrogenation of aromatic diamine MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-06-30 US disclosed
EP-0394058-A1 Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-24 EP disclosed