Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493050 | 1.00 | ALDH1A1 (0.56) | ALDH1A1APLNRCYP3A4EPHX1HIF1A | |
| SCHEMBL28120055 | 0.93 | ALDH1A1 (0.50) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL9439902 | 0.93 | ALDH1A1 (0.50) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL28853844 | 0.93 | ALDH1A1 (0.50) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL21065562 | 0.93 | ALDH1A1 (0.50) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL150431 | 0.91 | ALDH1A1 (0.74) | ALDH1A1APLNRCYP3A4EPHX1HIF1A | |
| SCHEMBL20782935 | 0.91 | ALDH1A1 (0.60) | ALDH1A1APLNRCYP3A4EPHX1HIF1A | |
| Cyanate SCHEMBL28834574 | 0.89 | ALDH1A1 (0.46) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL12892708 | 0.87 | ALDH1A1 (0.45) | ALDH1A1APLNRCYP3A4 | |
| SCHEMBL21378 | 0.86 | ALDH1A1 (0.72) | ALDH1A1APLNRCYP3A4EPHX1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113866329-B | Method for detecting isocyanate potential genotoxic impurities in glimepiride tablets | 贵州天安药业股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116218221-A | Flame-retardant material and preparation method thereof | 常州市诺普新材料有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-113866329-A | Method for detecting isocyanate potential genotoxicity impurities in glimepiride tablet | 贵州天安药业股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-108299251-B | Preparation method of glimepiride impurity | 山东新华制药股份有限公司 | 2020-10-30 | — | — | CN | claimed |
| CN-108299251-A | The preparation method of Glimepiride impurity | 山东新华制药股份有限公司 | 2018-07-20 | — | — | CN | claimed |
| US-7132444-B2 | Process for the preparation of trans-3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl) amino]carbonyl]amino]sulfonyl] phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide | SUN PHARMACEUTICAL INDUSTRIES, LTD. (IN) | 2006-11-07 | — | — | US | claimed |
| US-20050070593-A1 | Novel process for the preparation of trans-3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl) amino]carbonyl] amino]sulfonyl] phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide | SUN PHARMACEUTICAL INDUSTRIES, LTD. (IN) | 2005-03-31 | — | — | US | claimed |
| WO-2003057131-A2 | NOVEL PROCESS FOR THE PREPARATION OF TRANS-3- ETHYL-2,5- DIHYDRO-4- METHYL-N-[2-[ 4-[[[[(4-METHYL CYCLOHEXYL) AMINO]CARBONYL] AMINO]SULFONYL] PHENYL]ETHYL] -2-OXO-1H-PYRROLE -1-CARBOXAMIDE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2003-07-17 | — | — | WO | claimed |
| EP-4747247-A1 | NOVEL FATTY ACID AMIDE HYDROLASE MODULATORS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026104221-A1 | PROCESS FOR PREPARING OF ORGANIC CARBAMOYL AZIDES | All4Labels Group GmbH (DE) | 2026-05-21 | — | — | WO | disclosed |
| CN-121779277-A | Preparation process of trans-4-methylcyclohexyl isocyanate | 杭州布朗生物医药科技有限公司 | 2026-04-03 | — | — | CN | disclosed |
| CN-121779277-A | Preparation process of trans-4-methylcyclohexyl isocyanate | 杭州布朗生物医药科技有限公司 | 2026-04-03 | — | — | CN | disclosed |
| US-12479850-B2 | Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-25 | — | — | US | disclosed |
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | HANGZHOU YIRUI PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-11-20 | — | — | US | disclosed |
| WO-2006103690-A1 | A NOVEL PROCESS FOR PREPARATION OF SUBSTANTIALLY PURE GLIMEPIRIDE | USV LIMITED (IN) | 2006-10-05 | — | — | WO | disclosed |
| EP-1594839-A2 | METHODE OF MANUFACTURING GLIMEPIRIDE AND THE RESPECTIVE INTERMEDIATE | Zentiva, A.S. (CZ) | 2005-11-16 | — | — | EP | disclosed |
| US-20050070593-A1 | Novel process for the preparation of trans-3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl) amino]carbonyl] amino]sulfonyl] phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide | SUN PHARMACEUTICAL INDUSTRIES, LTD. (IN) | 2005-03-31 | — | — | US | disclosed |
| WO-2004073585-A2 | METHODE OF MANUFACTURING GLIMEPIRIDE AND THE RESPECTIVE INTERMEDIATE | ZENTIVA, A. S. (CZ) | 2004-09-02 | — | — | WO | disclosed |
| WO-2003057131-A2 | NOVEL PROCESS FOR THE PREPARATION OF TRANS-3- ETHYL-2,5- DIHYDRO-4- METHYL-N-[2-[ 4-[[[[(4-METHYL CYCLOHEXYL) AMINO]CARBONYL] AMINO]SULFONYL] PHENYL]ETHYL] -2-OXO-1H-PYRROLE -1-CARBOXAMIDE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2003-07-17 | — | — | WO | disclosed |
| US-3962244-A | LOWERING OF BLOOD-SUGAR LEVELS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070593-A1 | Novel process for the preparation of trans-3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl) amino]carbonyl] amino]sulfonyl] phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide | ALDH18A1, PRMT3, CPS1 | ALDH1A1 1083/4885APLNR 1903/4885CYP3A4 14/4885 |
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | BDKRB1, BDKRB2, UTS2R | ALDH1A1 2190/4885APLNR 287/4885CYP3A4 753/4885 |
| US-12479850-B2 | Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof | MET, MERTK, AXL | ALDH1A1 3166/4885APLNR 1455/4885CYP3A4 3564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.