Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439942 | 1.00 | PTPN1 (0.53) | PTPN1PTPN2PTPN6APPTRPA1 | |
| SCHEMBL1884074 | 0.77 | AKR1C3 (0.54) | KDM4ETTRAKR1C3AKR1C2CA12 | |
| SCHEMBL5560892 | 0.75 | TTR (0.65) | KDM4ETTRCA12CA1CA2 | |
| SCHEMBL901061 | 0.75 | CYP3A4 (0.46) | PTPN1TTRAKR1C3AKR1C2PTGS2 | |
| SCHEMBL11580777 | 0.74 | CA1 (0.38) | TTRAKR1C3AKR1C2CA12CA1 | |
| SCHEMBL8827305 | 0.74 | RARG (0.39) | KDM4ETTRPTGS2NPC1MTOR | |
| SCHEMBL8827313 | 0.74 | RARG (0.39) | KDM4ETTRPTGS2NPC1MTOR | |
| SCHEMBL900864 | 0.73 | MAPT (0.48) | PTPN1KDM4EGAATTRAKR1C3 | |
| SCHEMBL27186159 | 0.73 | MCL1 (0.48) | TTRAKR1C3AKR1C2CA1CA2 | |
| SCHEMBL11336146 | 0.73 | TPMT (0.48) | KDM4ETTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364912-A | Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0475238-A2 | Mesogenic glycidyl esters | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |