SCHEMBL1884074

SCHEMBL1884074

O=C(O)c1c(Br)cc(Br)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.54
AKR1C2 P52895 2/20 0.54
AKR1C1 Q04828 2/20 0.54
AKR1C4 P17516 1/20 0.54
HSD17B10 Q99714 2/20 0.47
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TTR P02766 1/20 0.42
GPR35 Q9HC97 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
POLB P06746 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
ERN1 O75460 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
GLA P06280 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31424007 0.85 AKR1C3 (0.63) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL3857062 0.84 AKR1C4 (0.45) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL286849 0.84 AKR1C4 (0.45) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL901061 0.81 CYP3A4 (0.46) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL5560892 0.81 TTR (0.65) HSD17B10TSHRTDP1TTRPOLB
SCHEMBL11336146 0.79 TPMT (0.48) CYP3A4TTRKDM4EALDH1A1SMN1; SMN2
SCHEMBL27186159 0.79 MCL1 (0.48) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL900864 0.79 MAPT (0.48) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL4908339 0.78 CYP3A4 (0.46) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10
SCHEMBL28018954 0.78 TTR (0.42) AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119799320-A Organic narrow-band afterglow material based on halation benzene derivative and preparation and application methods thereof 中国科学院上海有机化学研究所 2025-04-11 CN claimed
CN-119253090-A Zn-I2Battery electrolyte and preparation method and application thereof 中国科学院大连化学物理研究所 2025-01-03 CN claimed
US-11760868-B2 Preparation method for a flame retardant polystyrene Useon (Nanjing) Extrusion Machinery Co., Ltd. (CN) 2023-09-19 US claimed
US-20230151199-A1 PREPARATION METHOD FOR A FLAME RETARDANT POLYSTYRENE USEON TECHNOLOGY LIMITED (CN) 2023-05-18 US claimed
CN-111589472-B Carboxyl-containing conjugated microporous polymer/TiO 2 Method for preparing composite material 齐齐哈尔大学 2022-11-29 CN claimed
CN-113896822-B Preparation method of high-efficiency flame-retardant polystyrene by applying bromine flame retardant containing active functional group 江苏越升科技股份有限公司 2022-10-04 CN claimed
CN-113896822-A Preparation method of high-efficiency flame-retardant polystyrene by applying bromine flame retardant containing active functional group 南京越升挤出机械有限公司 2022-01-07 CN claimed
CN-112920382-A In-situ method for preparing conjugated microporous polymer TiO2Method for compounding nano antibacterial agent 齐齐哈尔大学 2021-06-08 CN claimed
CN-111589472-A Carboxyl-containing conjugated microporous polymer/TiO2Method for preparing composite material 齐齐哈尔大学 2020-08-28 CN claimed
CN-110437055-A A kind of preparation method of 2,4,6- tribromo benzoic acid SHANGHAI ALADDIN BIOCHEMICAL TECH CO LTD 2019-11-12 CN claimed
US-7588878-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-09-15 US claimed
US-7553603-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-06-30 US claimed
US-20080311518-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
US-20080311517-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
EP-2003503-A1 Inkless printing paper and method Xerox Corporation (US) 2008-12-17 EP claimed
US-5066823-A Rearrangement reaction, contrast agent for radiology BRACCO INDUSTRIA CHEMICA S.P.A. (IT) 1991-11-19 US claimed
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2026-01-15 US disclosed
US-12458049-B2 Steviol glycoside solubility enhancers CARGILL, INCORPORATED (US) 2025-11-04 US disclosed
US-4473650-A Use of strong organic acid polyelectrolyte salts in test means, test device and method for determining the ionic strength or specific gravity of a liquid sample MILES LABORATORIES, INC. (US) 1984-09-25 US disclosed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458049-B2 Steviol glycoside solubility enhancers SI, TAS2R7, TAS2R31 AKR1C3 3982/4885AKR1C2 2515/4885AKR1C1 3166/4885
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS TAS2R7, TAS2R31, TAS2R40 AKR1C3 3766/4885AKR1C2 3178/4885AKR1C1 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.