Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 10/20 | 0.39 |
| ▸ | RARB | P10826 | 9/20 | 0.39 |
| ▸ | RARA | P10276 | 7/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439964 | 1.00 | PTGS1 (0.45) | PTGS1PTGS2ALOX5CYP3A4ACHE | |
| SCHEMBL9342916 | 0.79 | RARG (0.51) | CYP3A4RARGRARBRARARXRA | |
| SCHEMBL9342915 | 0.79 | RARG (0.51) | CYP3A4RARGRARBRARARXRA | |
| SCHEMBL8827305 | 0.78 | RARG (0.39) | PTGS1PTGS2CYP3A4MAPTRARG | |
| SCHEMBL8827313 | 0.78 | RARG (0.39) | PTGS1PTGS2CYP3A4MAPTRARG | |
| SCHEMBL9440089 | 0.77 | TTR (0.49) | PTGS1PTGS2ALOX5CYP3A4ACHE | |
| SCHEMBL9440090 | 0.77 | TTR (0.49) | PTGS1PTGS2ALOX5CYP3A4ACHE | |
| SCHEMBL69007 | 0.77 | TPMT (0.56) | CYP3A4ACHEMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2182990 | 0.75 | PTGS1 (0.70) | PTGS1PTGS2ALOX5CYP3A4NQO2 | |
| SCHEMBL2182986 | 0.75 | PTGS1 (0.70) | PTGS1PTGS2ALOX5CYP3A4NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364912-A | Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0475238-A2 | Mesogenic glycidyl esters | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |