Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.51 |
| ▸ | RARB | P10826 | 17/20 | 0.51 |
| ▸ | RARA | P10276 | 15/20 | 0.51 |
| ▸ | RXRA | P19793 | 5/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342915 | 1.00 | RARG (0.51) | RARGRARBRARARXRARXRB | |
| SCHEMBL901113 | 0.83 | ALDH1A1 (0.68) | RARGRARBRARARXRARXRB | |
| SCHEMBL901112 | 0.83 | ALDH1A1 (0.68) | RARGRARBRARARXRARXRB | |
| SCHEMBL8460959 | 0.80 | RARG (0.58) | RARGRARBRARARXRARXRB | |
| SCHEMBL8460955 | 0.80 | RARG (0.58) | RARGRARBRARARXRARXRB | |
| SCHEMBL9439964 | 0.79 | PTGS1 (0.45) | RARGRARBRARARXRARXRB | |
| SCHEMBL9439959 | 0.79 | PTGS1 (0.45) | RARGRARBRARARXRARXRB | |
| SCHEMBL901031 | 0.77 | ESR1 (0.78) | RARGRARBRARARXRAALDH1A1 | |
| SCHEMBL901029 | 0.77 | ESR1 (0.78) | RARGRARBRARARXRAALDH1A1 | |
| SCHEMBL901098 | 0.77 | ESR1 (0.78) | RARGRARBRARARXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342904-A | Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | disclosed |