SCHEMBL9440179

SCHEMBL9440179

CCCCN1CCCCCC1=S

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ TSHR P16473 2/20 0.34
▸ CNR2 P34972 1/20 0.33
▸ HRH3 Q9Y5N1 1/20 0.33
▸ ALDH1A1 P00352 4/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ THRB P10828 1/20 0.33
▸ RAB9A P51151 3/20 0.33
▸ LMNA P02545 2/20 0.33
▸ NOS1 P29475 2/20 0.33
▸ NOS2 P35228 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ NR2F2 P24468 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ SIGMAR1 Q99720 1/20 0.32
▸ NPC1 O15118 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9440237 0.98 MEN1 (0.48) MEN1KMT2ATSHRALDH1A1L3MBTL1
SCHEMBL9440202 0.92 MEN1 (0.41) MEN1KMT2AHRH3ALDH1A1RAB9A
SCHEMBL27064650 0.92 MEN1 (0.41) MEN1KMT2AHRH3ALDH1A1RAB9A
SCHEMBL4141905 0.92 MEN1 (0.41) MEN1KMT2AHRH3ALDH1A1RAB9A
SCHEMBL9440178 0.92 MEN1 (0.50) MEN1KMT2ATSHRALDH1A1L3MBTL1
SCHEMBL4143578 0.90 MEN1 (0.42) MEN1KMT2AALDH1A1RAB9ALMNA
SCHEMBL10512029 0.88 HRH3 (0.47) MEN1KMT2AHRH3KDM4E
SCHEMBL1956432 0.85 KMT2A (0.42) MEN1KMT2AALDH1A1L3MBTL1THRB
SCHEMBL474116 0.84 ALOX5 (0.46) MEN1KMT2AALDH1A1RAB9ALMNA
SCHEMBL9440188 0.84 ALOX5 (0.46) MEN1KMT2AALDH1A1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 — — US disclosed
EP-0325616-B1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS WHITBY RESEARCH INC (US) 1994-07-20 — — EP disclosed
US-5270346-A Penetration enhancers for transdermal delivery of systemic agents WHITBY RESEARCH, INC. (US) 1993-12-14 — — US disclosed
US-5256647-A Enhanced penetration of skin with antibiotic, bactericides WHITBY RESEARCH, INC. (US) 1993-10-26 — — US disclosed
US-5218113-A To enhance the penetration of physiologically active agent through the skin or other membrane WHITBY RESEARCH, INC. (US) 1993-06-08 — — US disclosed
EP-0257063-B1 COMPOSITIONS COMPRISING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USES WHITBY RESEARCH, Inc. (US) 1992-06-17 — — EP disclosed
US-4992422-A Enhanced penetration of skin, membranes WHITBY RESEARCH, INC. (US) 1991-02-12 — — US disclosed
EP-0325616-A4 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS. NELSON RES & DEV COMPANY (US) 1989-12-12 — — EP disclosed
EP-0325616-A1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS. NELSON RES & DEV (US) 1989-08-02 — — EP disclosed
WO-1988002626-A1 PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS NELSON RESEARCH AND DEVELOPMENT COMPANY (US) 1988-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH MEN1 4840/4885KMT2A 2718/4885TSHR 3371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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