SCHEMBL9440231

SCHEMBL9440231

CCCCCCC(C)C(=O)c1ccc(OC)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.55
TAS1R1 Q7RTX1 1/20 0.55
HTT P42858 3/20 0.51
LMNA P02545 2/20 0.51
MAPK1 P28482 2/20 0.51
RAB9A P51151 1/20 0.51
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
MAPT P10636 2/20 0.44
TP53 P04637 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SMPD1 P17405 4/20 0.44
SLC6A4 P31645 1/20 0.42
HRH3 Q9Y5N1 2/20 0.42
MGLL Q99685 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
ACHE P22303 1/20 0.41
HTR1A P08908 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17996478 0.84 HTT (0.59) TAS1R3TAS1R1HTTLMNAMAPK1
SCHEMBL10595213 0.83 GRIN2B (0.42) SMPD1MGLL
SCHEMBL9440064 0.83 GRIN2B (0.42) SMPD1MGLL
SCHEMBL25666938 0.82 SLC6A4 (0.55) TAS1R3TAS1R1MAPK1MAPTSMPD1
SCHEMBL18643842 0.81 THRA (0.54) TAS1R3TAS1R1HTTLMNAMAPK1
SCHEMBL2422109 0.80 TAS1R3 (0.55) TAS1R3TAS1R1HTTLMNAMAPK1
SCHEMBL2843396 0.79 HTT (0.60) TAS1R3TAS1R1HTTLMNAMAPK1
SCHEMBL10429577 0.79 RARB (0.49) LMNATHRATHRBTP53SMN1; SMN2
SCHEMBL9440242 0.78 HTT (0.52) TAS1R3TAS1R1HTTLMNARAB9A
SCHEMBL27457534 0.78 HTT (0.52) TAS1R3TAS1R1HTTLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0341686-B1 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORP (JP) 1994-08-17 EP disclosed
US-5098602-A Aromatic ester derivatives and fluorophenol ketones NIPPON MINING CO., LTD. (JP) 1992-03-24 US disclosed
EP-0341686-A2 Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements JAPAN ENERGY CORPORATION (JP) 1989-11-15 EP disclosed