SCHEMBL9440418

SCHEMBL9440418

Ic1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.50
MAOB P27338 3/20 0.50
HPGD P15428 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SLC6A4 P31645 1/20 0.42
CHRNA7 P36544 1/20 0.39
MAPK1 P28482 2/20 0.39
NR1H2 P55055 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
BCL2 P10415 1/20 0.38
MCL1 Q07820 1/20 0.38
HTR2C P28335 1/20 0.38
HTR6 P50406 1/20 0.38
MMP3 P08254 1/20 0.37
MMP8 P22894 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5887631 0.88 CYP3A4 (0.47) MAOAMAOBHPGDALDH1A1MAPT
Fluoride SCHEMBL28773061 0.85 CYP3A4 (0.45) MAOAMAOBHPGDALDH1A1MAPT
SCHEMBL23277364 0.85 MAOA (0.62) MAOAMAOBHPGDALDH1A1MAPT
SCHEMBL3891569 0.85 MAOA (0.62) MAOAMAOBHPGDALDH1A1MAPT
SCHEMBL795030 0.85 MAOA (0.62) MAOAMAOBHPGDALDH1A1MAPT
SCHEMBL3891151 0.85 MAOA (0.62) MAOAMAOBHPGDALDH1A1MAPT
Diphenylsulfane SCHEMBL28332331 0.82 HPGD (0.60) MAOAMAOBHPGDALDH1A1MAPT
Iodobenzene SCHEMBL10481789 0.82 APP (0.46) HPGDALDH1A1HSD17B10TSHRAPP
Diphenylsulfane SCHEMBL452 0.82 HPGD (0.60) MAOAMAOBHPGDALDH1A1MAPT
Diphenylsulfane SCHEMBL7109540 0.82 HPGD (0.60) MAOAMAOBHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216721-A1 ADHESIVE SHEET HAVING EXCELLENT ULTRAVIOLET BLOCKING FUNCTION, ADHESIVE COMPOSITION, AND DISPLAY DEVICE COMPRISING SAME LMS CO., LTD. (KR) 2020-07-09 US disclosed
WO-2016116504-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed
CN-105324240-A Transparent conductive laminated film, method for producing same, and touch panel NITTO DENKO CORP 2016-02-10 CN disclosed
CN-101687781-B Compound for photoacid generator and use its anti-corrosion agent composition, pattern formation method CENTRAL GLASS CO.,LTD. (JP) 2015-08-12 CN disclosed
CN-101687781-A Compound for photoacid generator, resist composition using the same, and pattern-forming method CENTRAL GLASS CO LTD 2010-03-31 CN disclosed
US-5276037-A Antiinflammatory agents, antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-04 US disclosed
US-5272173-A 5-lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-12-21 US disclosed
US-5225438-A Lipoxygenase inhibitors for antiinflammatory agents or antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-07-06 US disclosed
EP-0488602-A1 Aryl derivatives ZENECA LIMITED (GB) 1992-06-03 EP disclosed