Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743234 | 0.85 | HTT (0.53) | MAOBKDM4EPAMPOLBHTT | |
| SCHEMBL10619606 | 0.80 | MAOB (0.61) | MAOBKDM4EPAMKMT2AMEN1 | |
| SCHEMBL1694508 | 0.80 | MAOB (0.61) | MAOBKDM4EPAMKMT2AMEN1 | |
| SCHEMBL1582564 | 0.80 | MAOB (0.61) | MAOBKDM4EPAMKMT2AMEN1 | |
| SCHEMBL18025762 | 0.79 | MAOB (0.58) | MAOBKDM4EPAMIDO1RAB9A | |
| SCHEMBL4073166 | 0.79 | MAOB (0.58) | MAOBKDM4EPAMIDO1RAB9A | |
| SCHEMBL7144203 | 0.78 | MAOB (0.54) | MAOBKDM4EPAMHTTIDO1 | |
| SCHEMBL6158944 | 0.77 | MAOB (0.49) | MAOBKDM4EPAMHTTIDO1 | |
| SCHEMBL5152333 | 0.77 | MAOB (0.57) | MAOBKDM4EPAMPOLBKMT2A | |
| SCHEMBL2453746 | 0.77 | MAOB (0.57) | MAOBKDM4EPAMHTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439059-B1 | 1-Phenylalkyl-3-phenylurea derivative | MITSUBISHI CHEM IND (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5202351-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0439059-A2 | 1-Phenylalkyl-3-phenylurea derivative | Mitsubishi Chemical Corporation (JP) | 1991-07-31 | — | — | EP | disclosed |