Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | PAM | P19021 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025762 | 1.00 | MAOB (0.58) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL2770961 | 0.83 | KDM4E (0.55) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL2770965 | 0.83 | KDM4E (0.55) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL14275030 | 0.79 | KDM4E (0.52) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL5814002 | 0.79 | KDM4E (0.52) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL11445050 | 0.79 | IDO1 (0.52) | MAOBPAMKDM4EIDO1HTR2A | |
| SCHEMBL1444030 | 0.79 | IDO1 (0.52) | MAOBPAMKDM4EIDO1HTR2A | |
| SCHEMBL6114073 | 0.79 | KDM4E (0.52) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL11597360 | 0.79 | PRMT1 (0.55) | MAOBPAMKDM4EIDO1ALDH1A1 | |
| SCHEMBL2189821 | 0.79 | KDM4E (0.52) | MAOBPAMKDM4EIDO1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510948-A1 | N-Hydroxy ureae as 5-lipoxygenase inhibitors | ELI LILLY AND COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| EP-2078721-B1 | Thieno-pyrimidine compounds having fungicidal activity | DOW AGROSCIENCES LLC (US) | 2014-01-22 | — | — | EP | disclosed |
| EP-2078721-A2 | Thieno-pyrimidime compounds having fungicidal activity | Dow AgroSciences LLC (US) | 2009-07-15 | — | — | EP | disclosed |
| US-7531482-B2 | Thieno-pyrimidine compounds having fungicidal activity | DOW AGROSCIENCES LLC (US) | 2009-05-12 | — | — | US | disclosed |
| EP-1937691-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2008-07-02 | — | — | EP | disclosed |
| US-20070093498-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2007-04-26 | — | — | US | disclosed |
| WO-2007046809-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2007-04-26 | — | — | WO | disclosed |
| US-5283361-A | Treating asthma, arthritis, allergy, psoriasis, shock, adult respiratory distress syndrome, ischemia, inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0510948-A1 | N-Hydroxy ureae as 5-lipoxygenase inhibitors | ELI LILLY AND COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| EP-0104888-B1 | PROCESS FOR PREPARING 2-HYDROXY-2-PHENYLETHYLAMINES | ELI LILLY AND COMPANY (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4391805-A | FUNGICIDES, ANTIPROTOZOA AGENTS, BACTERICIDWS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| EP-0050298-A2 | 1-(1,3-Dioxolan-2-ylmethyl) azoles, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093498-A1 | Thieno-pyrimidine compounds having fungicidal activity | TYMP, DPM1, TYMS | MAOB 340/4885PAM 1653/4885KDM4E 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.