SCHEMBL18025762

SCHEMBL18025762

ONC/C=C/c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.58
PAM P19021 1/20 0.54
KDM4E B2RXH2 1/20 0.53
IDO1 P14902 2/20 0.48
ALDH1A1 P00352 1/20 0.46
HTR2A P28223 3/20 0.45
RAB9A P51151 1/20 0.45
EGFR P00533 1/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MAOA P21397 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4073166 1.00 MAOB (0.58) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL2770961 0.83 KDM4E (0.55) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL2770965 0.83 KDM4E (0.55) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL14275030 0.79 KDM4E (0.52) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL5814002 0.79 KDM4E (0.52) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL11445050 0.79 IDO1 (0.52) MAOBPAMKDM4EIDO1HTR2A
SCHEMBL1444030 0.79 IDO1 (0.52) MAOBPAMKDM4EIDO1HTR2A
SCHEMBL6114073 0.79 KDM4E (0.52) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL11597360 0.79 PRMT1 (0.55) MAOBPAMKDM4EIDO1ALDH1A1
SCHEMBL2189821 0.79 KDM4E (0.52) MAOBPAMKDM4EIDO1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016133217-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE OXINDOLE COMPOUND AND TRIAZOLIUM SALT USED THEREIN AS CATALYST 国立大学法人名古屋大学 2016-08-25 WO disclosed