Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096756 | 0.89 | SLC2A1 (0.46) | CYP19A1SLC2A1TPMT | |
| SCHEMBL9050608 | 0.87 | CYP19A1 (0.54) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2857255 | 0.85 | KIF11 (0.42) | CYP19A1KIF11CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL1332873 | 0.84 | CYP19A1 (0.50) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL700 | 0.84 | CYP19A1 (0.50) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL456603 | 0.84 | CYP19A1 (0.50) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL1565321 | 0.81 | CYP19A1 (0.48) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL1101236 | 0.81 | CYP1A2 (0.50) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| Triphenylmethanol SCHEMBL29446231 | 0.81 | CYP19A1 (0.48) | CYP19A1SLC2A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21842336 | 0.79 | CYP2C9 (0.54) | CYP19A1KIF11SLC2A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276037-A | Antiinflammatory agents, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5272173-A | 5-lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-21 | — | — | US | disclosed |
| US-5225438-A | Lipoxygenase inhibitors for antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0488602-A1 | Aryl derivatives | ZENECA LIMITED (GB) | 1992-06-03 | — | — | EP | disclosed |