Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL10708791 | 0.91 | LMNA (0.57) | LMNATDP1THRBSOAT1ALDH1A1 | |
| Butanone SCHEMBL9440666 | 0.86 | LMNA (0.57) | LMNATDP1THRBSOAT1ALDH1A1 | |
| Acetone SCHEMBL3833129 | 0.85 | LMNA (0.63) | LMNATDP1THRBSOAT1ALDH1A1 | |
| Ethylene SCHEMBL4935788 | 0.82 | LMNA (0.75) | LMNATHRB | |
| Ethylene SCHEMBL3362390 | 0.82 | LMNA (0.86) | LMNATHRB | |
| Ethylene SCHEMBL555416 | 0.82 | LMNA (0.86) | LMNATHRB | |
| Ethylene SCHEMBL7713889 | 0.80 | LMNA (0.50) | LMNA | |
| Butanone SCHEMBL3163812 | 0.80 | LMNA (0.63) | LMNATDP1THRBSOAT1ALDH1A1 | |
| Propionic Acid SCHEMBL8820914 | 0.80 | LMNA (0.63) | LMNATDP1THRBSOAT1ALDH1A1 | |
| Acetone SCHEMBL590699 | 0.79 | LMNA (0.71) | LMNATDP1THRBSOAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359055-A | Chemical intermediate for vitamin D3 | KURARAY CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0321572-B1 | PREGNANE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KURARAY CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-5112998-A | Intermediates for vitamin D3 | KURARAY CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0321572-A1 | PREGNANE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KURARAY CO., LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |