Ethylene

Ethylene

SCHEMBL7713889

C=C.CCOC(C)OCC.O=C(O)CC(=O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31
GABRA4 P48169 2/20 0.31
GABRE P78334 2/20 0.31
GABRA6 Q16445 2/20 0.31
GABRG1 Q8N1C3 2/20 0.31
GABRG3 Q99928 2/20 0.31
GABRQ Q9UN88 2/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL7712117 0.82 LMNA (0.48) LMNAEPHX1MGAMGAASI
Ethylene SCHEMBL9440964 0.80 LMNA (0.57) LMNA
Propionic Acid SCHEMBL8820914 0.80 LMNA (0.63) LMNAGABRPGABRDGABRA1GABRB1
Acetone SCHEMBL3833129 0.80 LMNA (0.63) LMNAMGAMGAASIMGAM2
Bicarbonate SCHEMBL5374586 0.79 LMNA (0.71) LMNAGABRPGABRDGABRA1GABRB1
Bicarbonate SCHEMBL28942687 0.79 LMNA (0.71) LMNAGABRPGABRDGABRA1GABRB1
Bicarbonate SCHEMBL28895866 0.79 LMNA (0.71) LMNAGABRPGABRDGABRA1GABRB1
Glycolic Acid SCHEMBL5469101 0.78 LMNA (0.60) LMNAGABRPGABRDGABRA1GABRB1
Acetic Acid SCHEMBL23907968 0.77 LMNA (0.67) LMNAGABRPGABRDGABRA1GABRB1
Acetic Acid SCHEMBL222953 0.77 LMNA (0.67) LMNAGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372800-B1 IMMUNOSUPPRESSIVE EFFECT AND IS USEFUL AS AN INHIBITOR FOR THE REJECTION REACTION OCCURRING IN ORGAN OR BONE MARROW TRANSPLANTATION, AND AS A PREVENTIVE OR REMEDY FOR ARTICULAR RHEUMATISM, ATOPIC ECZEMA (DERMATITIS), BEHCET'S DISEASE, MITSUBISHI PHARMA CORPORATION (JP) 2002-04-16 US disclosed
US-6187821-B1 SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES WELFIDE CORPORATION (JP) 2001-02-13 US disclosed
US-5948820-A IMMUNOSUPPRESSANT; PREVENT REJECTION OF ORGAN TRANSPLANT;AUTOIMMUNE DISEASES; MULTIPLE SCLEROSIS; LUPUS; ANTIALLERGENS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-09-07 US disclosed