Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441753 | 0.87 | ALDH1A1 (0.32) | HMGCR | |
| SCHEMBL9441616 | 0.85 | HMGCR (0.48) | HMGCR | |
| SCHEMBL6949271 | 0.85 | HMGCR (0.49) | HMGCR | |
| SCHEMBL8952835 | 0.83 | — | — | |
| SCHEMBL8953003 | 0.83 | — | — | |
| SCHEMBL9853863 | 0.82 | HMGCR (0.30) | HMGCR | |
| SCHEMBL9781040 | 0.82 | HMGCR (0.30) | HMGCR | |
| SCHEMBL8952839 | 0.82 | — | — | |
| SCHEMBL9655519 | 0.82 | HMGCR (0.35) | HMGCR | |
| SCHEMBL8952998 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276021-A | Anticholesterol or antilipemic agents | E. R. SQUIBB & SONS, INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5091378-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-02-25 | — | — | US | disclosed |