Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.77 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.77 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.77 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.77 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.77 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.77 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.77 |
| ▸ | F7 | P08709 | 2/20 | 0.61 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | MAP2 | P11137 | 3/20 | 0.49 |
| ▸ | RHEB | Q15382 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441971 | 0.87 | GRIN1 (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL1504031 | 0.82 | MEN1 (0.77) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9441948 | 0.81 | GRIN2D (0.55) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9441947 | 0.81 | KDM4E (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL28173782 | 0.79 | F7 (0.58) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL720582 | 0.76 | F7 (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL6921825 | 0.75 | F7 (0.96) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL9441950 | 0.73 | GRIN1 (0.57) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL30310328 | 0.73 | F7 (0.74) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL671001 | 0.73 | F7 (0.74) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250541-A | Neurological disorders | FIDIA S.P.A. (IT) | 1993-10-05 | — | — | US | disclosed |
| WO-1991001973-A1 | KYNURENIC ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FIDIA S.P.A. (IT) | 1991-02-21 | — | — | WO | disclosed |