Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.74 |
| ▸ | F3 | P13726 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.61 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.61 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671001 | 1.00 | F7 (0.74) | F7F3ALOX15KDM4EHPGD | |
| SCHEMBL30071319 | 0.86 | F7 (0.61) | F7F3ALOX15KDM4EHPGD | |
| SCHEMBL3500068 | 0.86 | F7 (0.61) | F7F3ALOX15KDM4EHPGD | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL720582 | 0.85 | F7 (1.00) | F7F3KDM4EHPGDMEN1 | |
| SCHEMBL23835754 | 0.84 | ALOX15 (0.69) | F7F3ALOX15KDM4EHPGD | |
| 5-Chloroindole-2-Carboxylic Acid SCHEMBL6921825 | 0.84 | F7 (0.96) | F7F3KDM4EHPGDMEN1 | |
| SCHEMBL29062810 | 0.84 | ALOX15 (0.64) | F7F3ALOX15KDM4EHPGD | |
| SCHEMBL6170605 | 0.82 | MEN1 (0.78) | F7F3ALOX15MEN1CYP2C9 | |
| SCHEMBL16795745 | 0.81 | ALOX15 (0.61) | F7F3ALOX15MEN1MAPK1 | |
| SCHEMBL6170035 | 0.81 | MEN1 (0.63) | F7F3ALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086350-A1 | ALKYNE-CONTAINING ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |