Acetoacetic Acid

Acetoacetic Acid

SCHEMBL944288

C=C(CC(C)O)C(=O)O.CC(=O)CC(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.45
TET3 O43151 1/20 0.45
TET1 Q8NFU7 1/20 0.45
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
GRM1 Q13255 1/20 0.39
GRM2 Q14416 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL20506726 0.88 ALOX15 (0.52) TET2TET3TET1GRIK1GRIK2
Acetone SCHEMBL29420356 0.86 TET2 (0.54) TET2TET3TET1GRIK1GRIK2
SCHEMBL36381 0.85
Acetoacetic Acid SCHEMBL5494228 0.81 SLC22A6 (0.42) ALDH1A1TDP1KDM4EKDM6BKDM5C
Acetoacetic Acid SCHEMBL9682195 0.81 SLC22A6 (0.42) ALDH1A1TDP1KDM4EKDM6BKDM5C
Acetoacetic Acid SCHEMBL571326 0.81 SLC22A6 (0.42) ALDH1A1TDP1KDM4EKDM6BKDM5C
Acetoacetic Acid SCHEMBL5799898 0.78 TDP1 (0.40) ALOX15HSD17B10ALDH1A1TDP1KDM4E
SCHEMBL21815496 0.78 TET2 (0.47) TET2TET3TET1GRIK1GRIK2
Phosphoric Acid SCHEMBL27950593 0.78 TET2 (0.50) TET2TET3TET1GRIK1GRIK2
Acetoacetic Acid SCHEMBL6837513 0.76 KDM4E (0.46) ALDH1A1TDP1KDM4EKDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797644-B1 REMOVABLE PRESSURE SENSITIVE ADHESIVE AND ARTICLE MINNESOTA MINING & MFG (US) 2002-05-22 EP claimed
US-20240166785-A1 CATECHOL CONTAINING POLYMER EMULSIONS AND METHODS OF PREPARATION THEREOF THE UNIVERSITY OF AKRON 2024-05-23 US disclosed
US-11952505-B1 One component self-crosslinking coatings SWIMC LLC (US) 2024-04-09 US disclosed
US-11912901-B1 Polymer latex for matte films SWIMC LLC (US) 2024-02-27 US disclosed
US-11820845-B2 Polyamine additive LUBRIZOL ADVANCED MATERIALS, INC (US) 2023-11-21 US disclosed
WO-2023086924-A1 COMPOSITE PARTICLES FOR WATER-BASED COATING COMPOSITIONS SWIMC LLC (US) 2023-05-19 WO disclosed
US-11572489-B1 One component self-crosslinking coatings SWIMC LLC (US) 2023-02-07 US disclosed
US-20220033638-A1 Fast Drying Waterborne Coatings LUBRIZOL ADVANCED MATERIALS, INC. 2022-02-03 US disclosed
US-20210395417-A1 POLYAMINE ADDITIVE LUBRIZOL ADVANCED MATERIALS, INC. 2021-12-23 US disclosed
EP-3856850-A1 FAST DRYING WATERBORNE COATINGS Lubrizol Advanced Materials, Inc. (US) 2021-08-04 EP disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
EP-0179267-B1 PROCESS FOR REDUCING THE PERMEABILITY OF BLOW-MOULDED HOLLOW ARTICLES OF THERMOPLASTIC RESINS BASF Aktiengesellschaft (DE) 1989-07-19 EP disclosed
EP-0219796-A2 Sealing mass based on dispersed copolymerisates with an adhesion and higher resetting capacity BASF Aktiengesellschaft (DE) 1987-04-29 EP disclosed
EP-0127834-B1 STICKER DISPERSIONS FOR PRODUCING SELF-ADHESIVE ARTICLES, E.G. WITH POLYOLEFINIC CARRIERS BASF Aktiengesellschaft (DE) 1986-11-12 EP disclosed
EP-0179267-A2 Process for reducing the permeability of blow-moulded hollow articles of thermoplastic resins BASF Aktiengesellschaft (DE) 1986-04-30 EP disclosed
EP-0127834-A1 Sticker dispersions for producing self-adhesive articles, e.g. with polyolefinic carriers BASF Aktiengesellschaft (DE) 1984-12-12 EP disclosed
US-4267091-A COMPRIZING ACRYLIC COPOLYMER EMULSIONS, DIHYDRAZINE COMPOUNDS AND WATER SOLUBLE METAL SALTS BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed