SCHEMBL9443155

SCHEMBL9443155

CC(C)(C)C(O)(/C=C\c1ccc(Cl)cc1)Cn1cncn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
CYP3A4 P08684 2/20 0.56
KMT2A Q03164 4/20 0.49
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.44
HSP90AA1 P07900 3/20 0.41
POLB P06746 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HTT P42858 2/20 0.39
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.37
FDPS P14324 1/20 0.37
LMNA P02545 1/20 0.36
CYP19A1 P11511 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9443020 1.00 ALDH1A1 (0.56) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL9443025 1.00 ALDH1A1 (0.56) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL1284632 0.89 CYP3A4 (0.43) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL1284634 0.89 CYP3A4 (0.43) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL9788463 0.88 KMT2A (0.49) ALDH1A1CYP3A4KMT2AHSP90AA1SMN1; SMN2
SCHEMBL9788438 0.88 KMT2A (0.49) ALDH1A1CYP3A4KMT2AHSP90AA1SMN1; SMN2
SCHEMBL10474897 0.84 CYP3A4 (0.46) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL10829620 0.84 CYP3A4 (0.45) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL10829617 0.84 CYP3A4 (0.45) ALDH1A1CYP3A4KMT2ARAB9AATM
SCHEMBL10744398 0.82 ALDH1A1 (0.41) ALDH1A1CYP3A4KMT2ARAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250560-A Fungicidal agents BAYER AKTIENGESELLSCHAFT (DE) 1993-10-05 US disclosed
US-5240952-A Synergistic mixture BAYER AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
US-5198231-A Substituted 1-Hydroxyethyltriazole, Wettable Sulfur BAYER AKTIENGESELLSCHAFT (DE) 1993-03-30 US disclosed
US-5147887-A Synergistic mixtures of substituted triazoles and benzimidazoles BAYER AKTIENGESELLSCHAFT (DE) 1992-09-15 US disclosed
US-5137903-A Synergistic mixture of a 1-hydroxyethyl triazole and a triazine derivative BAYER AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
US-5082855-A Synergistic triazole and guanidine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1992-01-21 US disclosed
US-5063241-A FUNGICIDAL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-05 US disclosed
US-4990527-A Synergistic mixture of 1-(4-chlorophenyl-3-hydroxy-3-(1H-1,2,4 -triazol-1-yl)-3-tert-butyl-butane and Procymidone BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4985452-A 1-/Hydroxyethyl/triazoles, N-//trichloromethyl/thio/phthalimide, Synergistic BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed
US-4970223-A SYNERGISTIC 1,2,4-TRIAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-13 US disclosed
US-4933337-A Fungicidal agents BAYER AKTIENGESELLSCHAFT (DE) 1990-06-12 US disclosed
US-4845112-A SYNERGISTIC MIXTURE BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
US-4845111-A TRIAZOLE AND IMIDAZOLE BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0135854-A2 Fungicidal agents BAYER AG (DE) 1985-04-03 EP disclosed