Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284632 | 1.00 | CYP3A4 (0.43) | CYP3A4ALDH1A1HSP90AA1CYP2C19CYP1A2 | |
| SCHEMBL9788463 | 0.89 | KMT2A (0.49) | CYP3A4ALDH1A1HSP90AA1CYP2C19CYP1A2 | |
| SCHEMBL9443155 | 0.89 | ALDH1A1 (0.56) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL9788438 | 0.89 | KMT2A (0.49) | CYP3A4ALDH1A1HSP90AA1CYP2C19CYP1A2 | |
| SCHEMBL9443025 | 0.89 | ALDH1A1 (0.56) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL9443020 | 0.89 | ALDH1A1 (0.56) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL10744398 | 0.83 | ALDH1A1 (0.41) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL10745733 | 0.82 | CYP3A4 (0.37) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL10745738 | 0.82 | CYP3A4 (0.37) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS | |
| SCHEMBL10518216 | 0.81 | CYP3A4 (0.40) | CYP3A4ALDH1A1HSP90AA1CYP2C19FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443099-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146113-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
| US-5041459-A | Plant diseases; protection of industrial materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |
| EP-0405264-A1 | Hydroxy-keto-azoles | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | STS, TST, ERG28 | CYP3A4 49/4885ALDH1A1 1568/4885HSP90AA1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.