SCHEMBL9443286

SCHEMBL9443286

CC(C)C(=O)OCC(C)(C)C(O)C(C)C.CC(C)C(O)C(C)(C)CO

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
TRPA1 O75762 1/20 0.33
PTGS1 P23219 1/20 0.31
KCNH2 Q12809 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56321 0.93 TRPA1 (0.36) ALDH1A1POLBMAPTTRPA1HTT
Ethylene Glycol SCHEMBL28328525 0.91 TRPA1 (0.33) ALDH1A1POLBMAPTTRPA1HTT
SCHEMBL9443359 0.89 ALDH1A1 (0.30) ALDH1A1POLBMAPT
SCHEMBL28229215 0.87 TRPA1 (0.37) ALDH1A1POLBMAPTTRPA1HTT
Oxirane SCHEMBL11304757 0.84 TRPA1 (0.32) ALDH1A1POLBMAPTTRPA1
Isobutyraldehyde SCHEMBL10428140 0.84 TRPA1 (0.32) ALDH1A1POLBMAPTTRPA1
SCHEMBL28797536 0.84 TSHR (0.36) ALDH1A1POLBMAPTTRPA1
Propionic Acid SCHEMBL2795052 0.84 TRPA1 (0.35) ALDH1A1POLBMAPTTRPA1
SCHEMBL11860214 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL4837812 0.82 TRPA1 (0.33) TRPA1PTGS1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210066-A Acrylamide polymer emulsion binder, durability MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-11 US claimed