⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434990 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11820007 | 0.97 | — | — | |
| SCHEMBL3739659 | 0.75 | — | — | |
| SCHEMBL4835244 | 0.73 | — | — | |
| Sulfuric Acid SCHEMBL28140841 | 0.73 | CA5A (0.38) | — | |
| SCHEMBL708131 | 0.69 | CA5A (0.35) | — | |
| SCHEMBL248160 | 0.69 | — | — | |
| SCHEMBL27207893 | 0.67 | — | — | |
| SCHEMBL31464247 | 0.67 | — | — | |
| SCHEMBL491268 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448930-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2012-05-09 | — | — | EP | claimed |
| WO-2011001419-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV (IL) | 2011-01-06 | — | — | WO | claimed |
| JP-63303920-A | — | — | None | — | — | JP | disclosed |
| US-10103384-B2 | Electroactive polymers, manufacturing process thereof, electrode and use thereof | EVONIK DEGUSSA GMBH (DE) | 2018-10-16 | — | — | US | disclosed |
| EP-3019541-B1 | ELECTROACTIVE POLYMERS, MANUFACTURING PROCESS THEREOF, ELECTRODE AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2018-09-19 | — | — | EP | disclosed |
| EP-2448930-B1 | N-((S)-2-Oxo-tetrahydro-furan-3-yl)-amide derivatives as inhibitors of the bacterial quorum sensing for treating plant or animal diseases and for preventing the formation of biofilms on medical devices | THE NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2017-02-15 | — | — | EP | disclosed |
| US-20160233509-A1 | ELECTROACTIVE POLYMERS, MANUFACTURING PROCESS THEREOF, ELECTRODE AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| EP-3019541-A1 | ELECTROACTIVE POLYMERS, MANUFACTURING PROCESS THEREOF, ELECTRODE AND USE THEREOF | Evonik Degussa GmbH (DE) | 2016-05-18 | — | — | EP | disclosed |
| US-9242951-B2 | Covalent inhibition of bacterial quorum sensing | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2016-01-26 | — | — | US | disclosed |
| WO-2015003725-A1 | ELECTROACTIVE POLYMERS, MANUFACTURING PROCESS THEREOF, ELECTRODE AND USE THEREOF | FRIEDRICH-SCHILLER-UNIVERSITÄT JENA (DE) | 2015-01-15 | — | — | WO | disclosed |
| US-20140073690-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2014-03-13 | — | — | US | disclosed |
| EP-0379063-A2 | Process for preparing (trans)-4-substituted-DL-proline derivatives | E.R. SQUIBB & SONS, INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4937355-A | CYCLIZING PROTECTED AMINO ESTER WITH POTASSIUM AMIDE BASE, HYDROLYZING, REMOVING PROTECTIVE GROUP | E. R. SQUIBB & SONS, INC. (US) | 1990-06-26 | — | — | US | disclosed |
| JP-S63303920-A | COSMETIC CONTAINING HIGH MOLECULAR WEIGHT ULTRAVIOLET RAY ABSORBING AGENT | POLA CHEM IND INC | 1988-12-12 | — | — | JP | disclosed |
| EP-0154474-B1 | BIS(AMINOALKYL)PIPERAZINE DERIVATIVES AND THEIR USE AS METAL ION CONTROL AGENTS AND CEMENT SET RETARDING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4654387-A | NITRILE RUBBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-31 | — | — | US | disclosed |
| EP-0176197-A2 | Improved corrosion inhibition of metals in water systems | THE DOW CHEMICAL COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0154474-A2 | Bis(aminoalkyl)piperazine derivatives and their use as metal ion control agents and cement set retarding agents | THE DOW CHEMICAL COMPANY (US) | 1985-09-11 | — | — | EP | disclosed |
| US-4287342-A | 2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4188483-A | 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |