Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 6/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9305410 | 0.99 | BRD4 (0.49) | BRD4GRIN2BLTA4HADRB3DRD2 | |
| SCHEMBL9513902 | 0.97 | GRIN2B (0.48) | BRD4GRIN2BLTA4HADRB3DRD2 | |
| SCHEMBL9513968 | 0.96 | GRIN2B (0.47) | BRD4GRIN2BLTA4HADRB3DRD2 | |
| Hydrochloric Acid SCHEMBL9304455 | 0.96 | GRIN2B (0.47) | BRD4GRIN2BLTA4HADRB3DRD2 | |
| Hydrochloric Acid SCHEMBL9304774 | 0.95 | GRIN2B (0.47) | BRD4GRIN2BLTA4HADRB3DRD2 | |
| SCHEMBL9443702 | 0.89 | ADRB3 (0.56) | GRIN2BADRB3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9443699 | 0.89 | ADRB3 (0.56) | GRIN2BADRB3DRD2DRD3 | |
| SCHEMBL8765648 | 0.84 | ADRB3 (0.64) | GRIN2BADRB3 | |
| SCHEMBL5143758 | 0.84 | ADRB3 (0.64) | GRIN2BADRB3 | |
| Hydrochloric Acid SCHEMBL8765363 | 0.83 | ADRB3 (0.63) | GRIN2BADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | claimed |